Ultrasonic Dosage

Defining dosage

The landmark studies on therapeutic hypothermia have demonstrated an improved outcome in comatose patients after cardiac arrest targeting a temperature of 33°C for 24 hours [1,2]. The investigated temperature of 33°C was derived from the results of animal studies suggesting the best compromise between neuroprotection and adverse events. In the decade that followed, no randomized controlled tria...

Normal Dosage

Liquisolid Dosage System: A Novel Approach for Dosage formulation

Liquisolid system is a novel concept of dosage formulation for water insoluble drugs and lipophilic drugs via oral route. Formulation concept of liquisolid technology involves water insoluble drugs dissolved in suitable non-volatile liquid vehicles, and converted in to compact by blending with selective powder excipients. Liquisolid compacts are compressible powdered forms of liquid medications...

Gentamicin dosage intervals in neonates: longer dosage interval--less toxicity.

OBJECTIVES The aim of this study was to determine the incidence of toxic trough serum gentamicin levels in neonates in the first week of life, with different dosage intervals. METHODS This was a retrospective study of neonates born between 01.07.95 and 31.12.95, who received gentamicin. Data were collected on birth weight, gestation, gentamicin dose, the trough level of gentamicin, serum crea...

Ultrasonic Instrumentation